TY - JOUR
T1 - Differential diagnosis of illness in travelers arriving from sierra Leone, Liberia, or guinea
T2 - A cross-sectional study from the Geosentinel surveillance network
AU - GeoSentinel Surveillance Network
AU - Boggild, Andrea K.
AU - Esposito, Douglas H.
AU - Kozarsky, Phyllis E.
AU - Ansdell, Verno
AU - Beeching, Nicholas J.
AU - Campion, Danie
AU - Castelli, Francesc
AU - Caumes, Eri
AU - Chappuis, Francoi
AU - Cramer, Jakob P.
AU - Gkrania-Klotsas, Effrossyn
AU - Grobusch, Martin P.
AU - Hagmann, Stefan H.F.
AU - Hynes, Noreen A.
AU - Lian Lim, Po
AU - Lopez-Velez, Rogeli
AU - Malvy, Denis J.M.
AU - Mendelson, Mar
AU - Parola, Philipp
AU - Sotir, Mark J.
AU - Wu, Henry M.
AU - Hamer, Davidson H.
AU - Field, V.
AU - Libman, M. D.
AU - Rothe, C.
AU - Barnett, E. D.
AU - Schwartz, E.
AU - Gautret, P.
AU - von Sonnenburg, F.
AU - van Genderen, P.
AU - Jensenius, M.
AU - Stauffer, W. M.
AU - Mockenhaupt, F.
AU - Kain, K. C.
AU - Kanagawa, S.
AU - Coyle, C. M.
AU - Connor, B. A.
AU - Ursing, J.
AU - Leder, K.
AU - Haulman, J.
AU - Schlagenhauf, P.
AU - Vincelette, J.
AU - McCarthy, A.
AU - Pandey, P.
AU - Chen, L. H.
AU - Cahill, J. D.
AU - Rapp, C.
AU - Kendall, B.
AU - Lalloo, D.
AU - Yoshimura, Y.
PY - 2015/6/2
Y1 - 2015/6/2
N2 - Background: The largest-ever outbreak of Ebola virus disease (EVD), ongoing in West Africa since late 2013, has led to export of cases to Europe and North America. Clinicians encountering ill travelers arriving from countries with widespread Ebola virus transmission must be aware of alternate diagnoses associated with fever and other nonspecific symptoms. Objective: To define the spectrum of illness observed in persons returning from areas of West Africa where EVD transmission has been widespread. Design: Descriptive, using GeoSentinel records. Setting: 57 travel or tropical medicine clinics in 25 countries. Patients: 805 ill returned travelers and new immigrants from Sierra Leone, Liberia, or Guinea seen between September 2009 and August 2014. Measurements: Frequencies of demographic and travelrelated characteristics and illnesses reported. Results: The most common specific diagnosis among 770 nonimmigrant travelers was malaria (n = 310 [40.3%]), with Plasmodium falciparum or severe malaria in 267 (86%) and non-P. falciparum malaria in 43 (14%). Acute diarrhea was the second most common diagnosis among nonimmigrant travelers (n= 95 [12.3%]). Such common diagnoses as upper respiratory tract infection, urinary tract infection, and influenza-like illness occurred in only 26, 9, and 7 returning travelers, respectively. Few instances of typhoid fever (n = 8), acute HIV infection (n = 5), and dengue (n = 2) were encountered.
AB - Background: The largest-ever outbreak of Ebola virus disease (EVD), ongoing in West Africa since late 2013, has led to export of cases to Europe and North America. Clinicians encountering ill travelers arriving from countries with widespread Ebola virus transmission must be aware of alternate diagnoses associated with fever and other nonspecific symptoms. Objective: To define the spectrum of illness observed in persons returning from areas of West Africa where EVD transmission has been widespread. Design: Descriptive, using GeoSentinel records. Setting: 57 travel or tropical medicine clinics in 25 countries. Patients: 805 ill returned travelers and new immigrants from Sierra Leone, Liberia, or Guinea seen between September 2009 and August 2014. Measurements: Frequencies of demographic and travelrelated characteristics and illnesses reported. Results: The most common specific diagnosis among 770 nonimmigrant travelers was malaria (n = 310 [40.3%]), with Plasmodium falciparum or severe malaria in 267 (86%) and non-P. falciparum malaria in 43 (14%). Acute diarrhea was the second most common diagnosis among nonimmigrant travelers (n= 95 [12.3%]). Such common diagnoses as upper respiratory tract infection, urinary tract infection, and influenza-like illness occurred in only 26, 9, and 7 returning travelers, respectively. Few instances of typhoid fever (n = 8), acute HIV infection (n = 5), and dengue (n = 2) were encountered.
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U2 - 10.7326/M15-0074
DO - 10.7326/M15-0074
M3 - Article
C2 - 25961811
AN - SCOPUS:84932136659
SN - 0003-4819
VL - 162
SP - 757
EP - 764
JO - Annals of internal medicine
JF - Annals of internal medicine
IS - 11
ER -
