Differential-absorption photoacoustic imaging

Sheng Wen Huang, Janet F. Eary, Congxian Jia, Lingyun Huang, Shai Ashkenazi, Matthew O'Donnell

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


We present differential-absorption photoacoustic imaging, which detects the difference between transient and ground-state absorption, for contrast enhancement based on suppressing undesired objects. Two tubes were imaged. One contains a Pt(II) octaethylporphine (PtOEP) dye solution and serves as an object of interest, while the other contains an IR-783 (from Sigma-Aldrich) dye solution and serves as an object to suppress. Although the IR-783 tube dominates the conventional photoacoustic image, it is suppressed by 43 dB and consequently significantly overwhelmed by the PtOEP tube in the differential-absorption photoacoustic image. Imaging depth in this mode is also discussed.

Original languageEnglish (US)
Pages (from-to)2393-2395
Number of pages3
JournalOptics Letters
Issue number16
StatePublished - Aug 15 2009


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