Differential-absorption photoacoustic imaging

Sheng Wen Huang; Janet F. Eary; Congxian Jia; Lingyun Huang; Shai Ashkenazi; Matthew O'Donnell

doi:10.1364/OL.34.002393

Differential-absorption photoacoustic imaging

Sheng Wen Huang, Janet F. Eary, Congxian Jia, Lingyun Huang, Shai Ashkenazi, Matthew O'Donnell

Biomedical Engineering

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17 Scopus citations

Abstract

We present differential-absorption photoacoustic imaging, which detects the difference between transient and ground-state absorption, for contrast enhancement based on suppressing undesired objects. Two tubes were imaged. One contains a Pt(II) octaethylporphine (PtOEP) dye solution and serves as an object of interest, while the other contains an IR-783 (from Sigma-Aldrich) dye solution and serves as an object to suppress. Although the IR-783 tube dominates the conventional photoacoustic image, it is suppressed by 43 dB and consequently significantly overwhelmed by the PtOEP tube in the differential-absorption photoacoustic image. Imaging depth in this mode is also discussed.

Original language	English (US)
Pages (from-to)	2393-2395
Number of pages	3
Journal	Optics Letters
Volume	34
Issue number	16
DOIs	https://doi.org/10.1364/OL.34.002393
State	Published - Aug 15 2009

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AU - Eary, Janet F.

AU - Jia, Congxian

AU - Huang, Lingyun

AU - Ashkenazi, Shai

AU - O'Donnell, Matthew

PY - 2009/8/15

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AB - We present differential-absorption photoacoustic imaging, which detects the difference between transient and ground-state absorption, for contrast enhancement based on suppressing undesired objects. Two tubes were imaged. One contains a Pt(II) octaethylporphine (PtOEP) dye solution and serves as an object of interest, while the other contains an IR-783 (from Sigma-Aldrich) dye solution and serves as an object to suppress. Although the IR-783 tube dominates the conventional photoacoustic image, it is suppressed by 43 dB and consequently significantly overwhelmed by the PtOEP tube in the differential-absorption photoacoustic image. Imaging depth in this mode is also discussed.

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Differential-absorption photoacoustic imaging

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