Differences in reporting of perceived acute effects of alcohol use, marijuana use, and simultaneous alcohol and marijuana use

Christine M. Lee, Jennifer M. Cadigan, Megan E. Patrick

Research output: Contribution to journalArticlepeer-review

64 Scopus citations


Background Although there are serious negative harms associated with simultaneous alcohol and marijuana (SAM) use, little is known about the self-reported acute effects of SAM use and how they may be similar to or different than effects experienced when using alcohol or marijuana only. The current study examines the perceived acute effects of SAM use, compared to using alcohol or marijuana only, as well as demographic and substance use predictors of overall SAM effects. Methods Participants were a community sample of young adults ages 18–23 participating in a longitudinal study on social role transitions and substance use during young adulthood. Young adults who reported SAM use at least once in their lifetime were selected for the present analyses (N = 315; mean age = 21.42; 58% female) and reported the effects they experienced from typical alcohol use, marijuana use, and SAM use. Results There were significant differences in the extent to which young adults perceived the effects depending on the substances used. Most effects (i.e., clumsy, confused, dizzy, difficulty concentrating) were rated strongest when engaging in SAM use, compared to typical alcohol or marijuana use alone. Feeling high and feeling marijuana effects were rated strongest when engaging in marijuana use alone compared to SAM use, but feeling drunk was greater during SAM use compared to alcohol use alone. Greater alcohol use and increased time spent high during typical SAM use were associated with greater overall SAM effects. Conclusions When young adults engage in SAM use they report experiencing greater negative physiological and cognitive effects.

Original languageEnglish (US)
Pages (from-to)391-394
Number of pages4
JournalDrug and alcohol dependence
StatePublished - Nov 1 2017
Externally publishedYes

Bibliographical note

Funding Information:
Data collection and manuscript preparation were supported by a grant from the National Institute on Alcohol Abuse and Alcoholism ( R01AA022087 , PI: Christine M. Lee). Manuscript preparation was also supported by grant R01AA025037 ( MPI: Lee and Patrick ) and grant F32AA025263 ( PI: Cadigan ). The content of this manuscript is solely the responsibility of the author(s) and does not necessarily represent the official views of the National Institute on Alcohol Abuse and Alcoholism or the National Institutes of Health.

Publisher Copyright:
© 2017 Elsevier B.V.


  • Alcohol
  • Consequences
  • Marijuana
  • Simultaneous alcohol and marijuana (SAM) use
  • Subjective effects
  • Young adults


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