Abstract
Background: Previous studies on intake of linoleic acid (LA), the predominant n-6 fatty acid, and coronary heart disease (CHD) risk have generated inconsistent results. We performed a systematic review and meta-analysis of prospective cohort studies to summarize the evidence regarding the relation of dietary LA intake and CHD risk.
Conclusions: In prospective observational studies, dietary LA intake is inversely associated with CHD risk in a dose- response manner. These data provide support for current recommendations to replace saturated fat with polyunsaturated fat for primary prevention of CHD.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1568-1578 |
| Number of pages | 11 |
| Journal | Circulation |
| Volume | 130 |
| Issue number | 18 |
| DOIs | |
| State | Published - 2014 |
Bibliographical note
Publisher Copyright:© 2014 American Heart Association, Inc.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Cardiovascular disease
- Coronary disease
- Diet
- Linoleic acid
- Meta-analysis
- Polyunsaturated fatty acids
- Saturated fatty acids
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