Diet and Diabetic Kidney Disease: Plant Versus Animal Protein

Ranjani N Moorthi, Colby J Vorland, Kathleen M Hill Gallant

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations


PURPOSE OF REVIEW: The goal of this review is to present an overview of the evidence on the effectiveness of plant-based diets in delaying progression of diabetic kidney disease (DKD).

RECENT FINDINGS: The ideal quantity of dietary protein has been a controversial topic for patients with DKD. Smaller studies have focused on protein source, plant versus animal, for preventing progression. Limited evidence suggests that dietary patterns that focus on plant-based foods, those that are lower in processed foods, or those that are lower in advanced glycation end products (AGE) may be useful in prevention of DKD progression. Increasing plant-based foods, incorporating diet patterns that limit processed foods, or potentially lowering AGE contents in diets may be beneficial for dietary management of DKD. However, dietary studies specifically targeted at DKD treatment are sparse. Further, large trials powered to assess outcomes including changes in kidney function, end-stage kidney disease, and mortality are needed to provide more substantial evidence for these diets.

Original languageEnglish (US)
Pages (from-to)15
JournalCurrent diabetes reports
Issue number3
StatePublished - Mar 2017
Externally publishedYes


  • Animals
  • Diabetic Nephropathies/diet therapy
  • Dietary Proteins/administration & dosage
  • Disease Progression
  • Glycation End Products, Advanced/analysis
  • Humans
  • Kidney Failure, Chronic/diet therapy

PubMed: MeSH publication types

  • Comparative Study
  • Journal Article
  • Review


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