Dielectrophoretic focusing of particles in a microchannel constriction using DC-biased AC flectric fields

Junjie Zhu, Xiangchun Xuan

Research output: Contribution to journalArticlepeer-review

91 Scopus citations

Abstract

This paper presents a fundamental study of particle electrokinetic focusing in a single microchannel constriction. Through both experiments and simulations, we demonstrate that such dielectrophoresis-induced particle focusing can be implemented in a much smaller magnitude of DC-biased AC electric fields (10 kV/m in total) as compared to pure DC electric fields (up to 100 kV/m). This is attributed to the increase in the ratio of cross-stream particle dielectrophoretic velocity to streamwise electrokinetic velocity as only the DC field component contributes to the latter. The effects of the 1 kHz frequency AC to DC electric field ratio on particle trajectories and velocity variations through the microchannel constriction are also examined, which are found to agree with the simulation results.

Original languageEnglish (US)
Pages (from-to)2668-2675
Number of pages8
JournalELECTROPHORESIS
Volume30
Issue number15
DOIs
StatePublished - Aug 1 2009

Keywords

  • DC-biased AC electric field
  • Dielectrophoresis
  • Electrokinetic flow
  • Microchannel constriction
  • Particle focusing

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