TY - JOUR
T1 - Did Ulysses have porphyria?
AU - Pierach, Claus A
PY - 2004/7/1
Y1 - 2004/7/1
N2 - Although the biosynthetic pathway to heme has been well elucidated and errors along that route have been identified and firmly connected to specific diseases, the porphyrias, slight but nonspecific abnormalities, are occasionally invoked as proof of porphyria or in support of other diagnoses. An errant patient with a conundrum of symptoms but without an explanation for them might have to take iatrogenic detours only to learn after what are at times ulyssean vagaries that the initial diagnosis of porphyria is in the end untenable. Thus the porphyrias are superb examples of the interface between laboratory and clinical medicine, in which the occurrence of the Ulysses syndrome can be curtailed through the careful ordering of tests and cogent interpretation of their results.
AB - Although the biosynthetic pathway to heme has been well elucidated and errors along that route have been identified and firmly connected to specific diseases, the porphyrias, slight but nonspecific abnormalities, are occasionally invoked as proof of porphyria or in support of other diagnoses. An errant patient with a conundrum of symptoms but without an explanation for them might have to take iatrogenic detours only to learn after what are at times ulyssean vagaries that the initial diagnosis of porphyria is in the end untenable. Thus the porphyrias are superb examples of the interface between laboratory and clinical medicine, in which the occurrence of the Ulysses syndrome can be curtailed through the careful ordering of tests and cogent interpretation of their results.
UR - http://www.scopus.com/inward/record.url?scp=3142564426&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=3142564426&partnerID=8YFLogxK
U2 - 10.1016/j.lab.2003.09.007
DO - 10.1016/j.lab.2003.09.007
M3 - Review article
C2 - 15252401
AN - SCOPUS:3142564426
SN - 0022-2143
VL - 144
SP - 7
EP - 10
JO - Journal of Laboratory and Clinical Medicine
JF - Journal of Laboratory and Clinical Medicine
IS - 1
ER -