Diagnostic Exercise: Poor Performance in a Racehorse

F. Giannitti, R. Petrov, J. Parker, M. Booth, M. Anderson

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


A 9-year-old Thoroughbred gelding presented with a 97-day history of poor performance and intermittent fever. Clinicopathologic changes included increased serum activity of γ-glutamyltransferase and alkaline phosphatase, mild hyperbilirubinemia, and leukocytosis with neutrophilia and lymphopenia. Abdominal ultrasound revealed hepatomegaly with hyperechoic hepatic parenchyma and biliary distention. Pathologic findings included marked hepatomegaly (liver 3.6% of body weight), firm hepatic consistency with a diffuse enhanced reticular pattern, severe portal bridging and sinusoidal fibrosis, oval cell/bile duct hyperplasia, and bile stasis. The differential diagnoses and diagnostic workup to achieve the diagnosis are briefly discussed.

Original languageEnglish (US)
Pages (from-to)824-827
Number of pages4
JournalVeterinary pathology
Issue number4
StatePublished - Jul 1 2014
Externally publishedYes

Bibliographical note

Publisher Copyright:
© The Author(s) 2013.


  • Avena fatua (wild oat)
  • choledocholithiasis
  • choledochus
  • foreign body
  • horse
  • liver
  • obstruction


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