Diagnostic Exercise: Hemolysis and Sudden Death in Lambs

F. Giannitti, M. Macias Rioseco, J. P. García, J. Beingesser, L. W. Woods, B. Puschner, F. A. Uzal

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Within a 24-hour period, 7 out of 200 three- to four-week-old pastured Katahdin lambs died after showing clinical signs of hemoglobinuria, red-tinged feces, weakness, and recumbency. One of the lambs that was examined clinically before natural death also had abdominal pain, trembling, tachycardia, and severe anemia with a packed cell volume of 4%. Pathologic findings included icterus, hemoglobinuric nephrosis, dark red urine, pulmonary edema, hydrothorax, splenomegaly, and acute centrilobular to midzonal hepatocellular degeneration and necrosis with cholestasis. The differential diagnoses and diagnostic workup to achieve the diagnosis are briefly discussed.

Original languageEnglish (US)
Pages (from-to)624-627
Number of pages4
JournalVeterinary pathology
Issue number3
StatePublished - May 2014


  • Clostridium perfringens type D
  • alpha toxin
  • hemoglobinuria
  • icterus
  • yellow lamb disease


Dive into the research topics of 'Diagnostic Exercise: Hemolysis and Sudden Death in Lambs'. Together they form a unique fingerprint.

Cite this