Diabetes Prevention Program Translation in the Veterans Health Administration

Tannaz Moin, Laura J. Damschroder, Mona AuYoung, Matthew L. Maciejewski, Santanu K. Datta, Jane E. Weinreb, Nanette I. Steinle, Charles Billington, Maria Hughes, Fatima Makki, Robert G. Holleman, H. Myra Kim, Amy S. Jeffreys, Linda S. Kinsinger, Jennifer A. Burns, Caroline R. Richardson

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


Introduction This clinical demonstration trial compared the effectiveness of the Veterans Affairs Diabetes Prevention Program (VA-DPP) with an evidence-based usual care weight management program (MOVE!®) in the Veterans Health Administration health system. Design Prospective, pragmatic, non-randomized comparative effectiveness study of two behavioral weight management interventions. Setting/participants Obese/overweight Veterans with prediabetes were recruited from three geographically diverse VA sites between 2012 and 2014. Intervention VA-DPP included 22 group-based intensive lifestyle change sessions. Main outcome measures Weight change at 6 and 12 months, hemoglobin A1c (HbA1c) at 12 months, and VA health expenditure changes at 15 months were assessed using VA electronic health record and claims data. Between- and within-group comparisons for weight and HbA1c were done using linear mixed-effects models controlling for age, gender, race/ethnicity, baseline outcome values, and site. Analyses were conducted in 2015–2016. Results A total of 387 participants enrolled (273 VA-DPP, 114 MOVE!). More VA-DPP participants completed at least one (73.3% VA-DPP vs 57.5% MOVE! p=0.002); four (57.5% VA-DPP vs 42.5% MOVE!, p=0.007); and eight or more sessions (42.5% VA-DPP vs 31% MOVE!, p=0.035). Weight loss from baseline was significant at both 6 (p<0.001) and 12 months (p<0.001) for VA-DPP participants, but only significant at 6 months for MOVE! participants (p=0.004). Between groups, there were significant differences in 6-month weight loss (–4.1 kg VA-DPP vs –1.9 kg MOVE!, p<0.001), but not 12-month weight loss (–3.4 kg VA-DPP vs –2.0 kg MOVE!, p=0.16). There were no significant differences in HbA1c change or outpatient, inpatient, and total VA expenditures. Conclusions VA-DPP participants had higher participation rates and weight loss at 6 months, but similar weight, HbA1c, and health expenditures at 12 months compared to MOVE! participants. Features of VA-DPP may help enhance the capability of MOVE! to reach a larger proportion of the served population and promote individual-level weight maintenance.

Original languageEnglish (US)
Pages (from-to)70-77
Number of pages8
JournalAmerican journal of preventive medicine
Issue number1
StatePublished - Jul 2017

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© 2017


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