Developmental origins of breast cancer: A paternal perspective

Camile Castilho Fontelles, Raquel Santana da Cruz, Leena Hilakivi-Clarke, Sonia de Assis, Thomas Prates Ong

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


The developmental origins of breast cancer have been considered predominantly from a maternal perspective. Although accumulating evidence suggests a paternal programming effect on metabolic diseases, the potential impact of fathers’ experiences on their daughters’ breast cancer risk has received less attention. In this chapter, we focus on the developmental origins of breast cancer and examine the emerging evidence for a role of fathers’ experiences.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Number of pages13
StatePublished - 2018
Externally publishedYes

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745


  • Breast cancer
  • Female offspring
  • Paternal programming
  • Preconceptional diet

Fingerprint Dive into the research topics of 'Developmental origins of breast cancer: A paternal perspective'. Together they form a unique fingerprint.

  • Cite this

    Fontelles, C. C., da Cruz, R. S., Hilakivi-Clarke, L., de Assis, S., & Ong, T. P. (2018). Developmental origins of breast cancer: A paternal perspective. In Methods in Molecular Biology (pp. 91-103). (Methods in Molecular Biology; Vol. 1735). Humana Press Inc..