Developmental origins of breast cancer: A paternal perspective

Camile Castilho Fontelles, Raquel Santana da Cruz, Leena Hilakivi-Clarke, Sonia de Assis, Thomas Prates Ong

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Abstract

The developmental origins of breast cancer have been considered predominantly from a maternal perspective. Although accumulating evidence suggests a paternal programming effect on metabolic diseases, the potential impact of fathers’ experiences on their daughters’ breast cancer risk has received less attention. In this chapter, we focus on the developmental origins of breast cancer and examine the emerging evidence for a role of fathers’ experiences.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages91-103
Number of pages13
DOIs
StatePublished - 2018
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume1735
ISSN (Print)1064-3745

Bibliographical note

Funding Information:
C. C. F. was a recipient of a PhD scholarship from the Brazilian National Council for Scientific and Technological Development (CNPq; Proc. 153478/2012-8). T. P. O. is the recipient of a researcher fellowship from CNPq (Proc.307910/2016-4) and is supported by grants from CNPq (Proc. 448501/2014-7), the Food Research Center (FoRC), and the São Paulo State Research Funding Agency (Proc.2013/07914-8).

Publisher Copyright:
© 2018, Springer Science+Business Media, LLC.

Keywords

  • Breast cancer
  • Female offspring
  • Paternal programming
  • Preconceptional diet

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