Developmental changes in hepatic IGF-2 and IGFBP-2 mRNA levels in intrauterine growth-retarded and control swine

Kimberly A. Kampman, Timothy G. Ramsay, Michael E. White

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

1. 1. Significantly elevated levels of hepatic IGFBP-2 mRNA were detected in IUGR piglets at 90 days fetally and at birth (P < 0.05). 2. 2. Developmentally, hepatic IGF-2 (P < 0.05) and IGFBP-2 (P < 0.01) mRNA levels were higher fetally and at birth than at 21 and 49 days of age. 3. 3. This study provides new information concerning hepatic expression of IGF-2 and IGFBP-2 in developing swine.

Original languageEnglish (US)
Pages (from-to)415-421
Number of pages7
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume104
Issue number2
DOIs
StatePublished - Feb 1993

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