Developmental cannabidiol exposure increases anxiety and modifies genome-wide brain DNA methylation in adult female mice

Keyphrases

• Cannabidiol 100%
• Female Mice 100%
• Brain DNA Methylation 100%
• Adult Female 100%
• DNA Methylation (DNAm) 37%
• Agouti Viable Yellow 37%
• Epigenome 25%
• Coat Color 25%
• Direct Exposure 25%
• Color Shift 25%
• Older Adults 12%
• Molecular Mechanism 12%
• Antipsychotics 12%
• Antidepressants 12%
• Gene Regulation 12%
• Neurogenesis 12%
• Cannabinoids 12%
• Adulthood 12%
• Cannabis 12%
• Hippocampus 12%
• Substance Use 12%
• Human Studies 12%
• Cerebral Cortex 12%
• Negative Effects 12%
• Behavioral Outcomes 12%
• Sex-specific 12%
• Brain Regions 12%
• Lactation 12%
• Psychosocial Outcomes 12%
• Detrimental Effects 12%
• Phenotypic Effects 12%
• Memory Behavior 12%
• Embryogenesis 12%
• Environmental Inputs 12%
• Spatial Memory 12%
• Being Observed 12%
• Adult Offspring 12%
• F1 Progeny 12%
• Epigenetic Marks 12%
• Agouti 12%
• Impact-based 12%
• Anxiolytic 12%
• Compulsive Behavior 12%
• Developmental Exposure 12%
• Nulliparous Females 12%
• Relevant Term 12%
• Functional Enrichment 12%
• Reduced Representation Bisulfite Sequencing 12%
• Differentially Methylated Loci 12%
• Spatial Anxiety 12%
• Δ9-tetrahydrocannabinol (Δ9-THC) 12%
• Brain Epigenome 12%
• Epigenetic Perturbation 12%

Neuroscience

• DNA Methylation 100%
• Cannabidiol 100%
• Epigenome 37%
• Behavior (Neuroscience) 25%
• Substance Abuse 12%
• Hippocampus 12%
• Cerebral Cortex 12%
• Spatial Memory 12%
• Gene Control 12%
• Antidepressant 12%
• Compulsive Behavior 12%
• Cannabis 12%
• Neurogenesis 12%
• Psychotomimetic 12%
• Tetrahydrocannabinol 12%
• Cannabinoid 12%
• Antipsychotic 12%
• Brain Region 12%