Abstract
Development and characterization of a tissue-engineered cardiovascular valve, was analyzed. A biopolymer reconstituted into a hydrated network of native fibrils, such as type I collagen or more recently fibrin due to its ability to stimulate increased cell-secreted extracellular matrix (ECM). Appropriate cells are entrapped in this biopolymer network as it forms following injection of a cell suspension containing monomers into a mold. This mold impart proper geometry to the valve and also provide a constraint to cell-mediated network compaction resulting in aligned fibrils similar to that of native valves.
| Original language | English (US) |
|---|---|
| Title of host publication | Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products |
| Number of pages | 1 |
| State | Published - Dec 1 2002 |
| Event | Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products - Atlanta, GA, United States Duration: Oct 13 2002 → Oct 16 2002 |
Other
| Other | Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products |
|---|---|
| Country/Territory | United States |
| City | Atlanta, GA |
| Period | 10/13/02 → 10/16/02 |