Developing and describing a typology of lucid episodes among people with Alzheimer's disease and related dementias

  • Joan M. Griffin
  • , Kyungmin Kim
  • , Dawn M. Finnie
  • , Maria I. Lapid
  • , Joseph E. Gaugler
  • , Alexander Batthyány
  • , Lauren R. Bangerter
  • , Virginia S. Biggar
  • , Theresa Frangiosa

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

INTRODUCTION: This study examined lucid episodes among people living with late-stage Alzheimer's disease and related dementias (PLWD) and then developed a typology of these episodes to help characterize them. METHODS: Family caregivers of PLWD provided information about witnessed episodes, including proximity to death, cognitive status, duration, communication quality, and circumstances prior to lucid episodes on up to two episodes (caregiver N = 151; episode N = 279). Latent class analysis was used to classify and characterize empirically distinct clusters of lucid episodes. RESULTS: Four lucid episode types were identified. The most common type occurred during visits with family and among PLWD who lived > 6 months after the episode. The least common type coincided with family visits and occurred within 7 days of the PLWD's death. DISCUSSION: Findings suggest that multiple types of lucid episodes exist; not all signal impending death; and some, but not all, are precipitated by external stimuli.

Original languageEnglish (US)
Pages (from-to)2434-2443
Number of pages10
JournalAlzheimer's and Dementia
Volume20
Issue number4
DOIs
StatePublished - Apr 2024

Bibliographical note

Publisher Copyright:
© 2024 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.

Keywords

  • Alzheimer's disease and related dementias
  • family caregivers
  • lucidity
  • paradoxical lucidity

PubMed: MeSH publication types

  • Journal Article
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

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