Determination of metals at trace levels via pre-column derivatization and nonpolar stationary-phase high-performance liquid chromatography with n-butyl-2-naphthylmethyldithiocarbamate complexes

Young Tzung Shih, Peter W. Carr

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31 Scopus citations

Abstract

A new, very stable dithiocarbamate, bis(n-butyl-2-naphthylmethyldithiocarbamate) zinc(II), has been synthesized and its use in trace metal determination by high-performance liquid chromatography (h.p.l.c.) has been investigated. Metal complexes of this ligand are thermodynamically stable and kinetically inert at the 1 × 10-8 M level. Various metal complexes including nickel(II), iron(III), copper(II), mercury(II), and cobalt(II) have been "baseline" separated by nonpolar stationary-phase h.p.l.c. The detection limits are about 1-2 ng with a variable-wavelength absorbance detector.

Original languageEnglish (US)
Pages (from-to)55-62
Number of pages8
JournalAnalytica Chimica Acta
Volume142
Issue numberC
DOIs
StatePublished - Oct 1 1982

Bibliographical note

Funding Information:
This work was supported by a grant from the National Institute of Occupational Safety and Health (1 ROl OHOO876-01).

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