TY - JOUR
T1 - Determinants of stage at diagnosis of HPV-related cancer including area deprivation and clinical factors
AU - Chakravarthy, Rohini
AU - Stallings, Sarah C.
AU - Velez Edwards, Digna R.
AU - Zhao, Sifang Kathy
AU - Conway, Douglas
AU - Rao, J. Sunil
AU - Aldrich, Melinda C.
AU - Kobetz, Erin
AU - Wilkins, Consuelo H.
N1 - Publisher Copyright:
© 2021 The Author(s) 2021. Published by Oxford University Press on behalf of Faculty of Public Health.
PY - 2022/3/1
Y1 - 2022/3/1
N2 - Background: Collecting social determinants of health in electronic health records is time-consuming. Meanwhile, an Area Deprivation Index (ADI) aggregates sociodemographic information from census data. The objective of this study was to ascertain whether ADI is associated with stage of human papillomavirus (HPV)-related cancer at diagnosis. Methods: We tested for the association between the stage of HPV-related cancer presentation and ADI as well as the association between stage and the value of each census-based measure using ordered logistic regression, adjusting for age, race and sex. Results: Among 3247 cases of HPV-related cancers presenting to an urban academic medical center, the average age at diagnosis was 57. The average stage at diagnosis was Surveillance, Epidemiology and End Results Stage 3. In the study population, 43% of patients were female and 87% were white. In this study population, there was no association between stage of HPV-related cancer presentation and either aggregate or individual census variables. Conclusions: These results may reflect insufficient sample size, a lack of socio-demographic diversity in our population, or suggest that simplifying social determinants of health into a single geocoded index is not a reliable surrogate for assessing a patient's risk for HPV-related cancer.
AB - Background: Collecting social determinants of health in electronic health records is time-consuming. Meanwhile, an Area Deprivation Index (ADI) aggregates sociodemographic information from census data. The objective of this study was to ascertain whether ADI is associated with stage of human papillomavirus (HPV)-related cancer at diagnosis. Methods: We tested for the association between the stage of HPV-related cancer presentation and ADI as well as the association between stage and the value of each census-based measure using ordered logistic regression, adjusting for age, race and sex. Results: Among 3247 cases of HPV-related cancers presenting to an urban academic medical center, the average age at diagnosis was 57. The average stage at diagnosis was Surveillance, Epidemiology and End Results Stage 3. In the study population, 43% of patients were female and 87% were white. In this study population, there was no association between stage of HPV-related cancer presentation and either aggregate or individual census variables. Conclusions: These results may reflect insufficient sample size, a lack of socio-demographic diversity in our population, or suggest that simplifying social determinants of health into a single geocoded index is not a reliable surrogate for assessing a patient's risk for HPV-related cancer.
KW - cancer
KW - race
KW - social determinants
UR - https://www.scopus.com/pages/publications/85126072706
UR - https://www.scopus.com/inward/citedby.url?scp=85126072706&partnerID=8YFLogxK
U2 - 10.1093/pubmed/fdaa246
DO - 10.1093/pubmed/fdaa246
M3 - Article
C2 - 33512511
AN - SCOPUS:85126072706
SN - 1741-3842
VL - 44
SP - 18
EP - 27
JO - Journal of Public Health
JF - Journal of Public Health
IS - 1
ER -
