Determinants of motor polarity in the kinesin proteins

S. A. Endow, D. Cole, R. Cooke, M. Titus, G. Pollack

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Many of the proteins that are members of the kinesin family of microtubule motor proteins are plus-end motors; however, a few of the kinesin proteins have now been found to be minus-end microtubule motors. Overall structural features of the proteins can be used to identify further kinesins that are likely to be minus-end motors. Structural or biochemical differences that may serve as the basis of the 'reversed' polarity of a unique subset of the kinesin proteins are discussed.

Original languageEnglish (US)
Pages (from-to)271s-274s
JournalBiophysical journal
Issue number4 SUPPL.
StatePublished - 1995


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