Abstract
Two new diprenylquinones, glabruquinone A (desmethylubiquinone Q 2) having cancer preventive properties and its minor isomer Glabruquinone B were isolated from the ascidian Aplidium glabrum. Their structures have been elucidated by NMR and mass spectra and confirmed by synthesis.
Original language | English (US) |
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Pages (from-to) | 559-562 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 46 |
Issue number | 4 |
DOIs | |
State | Published - Jan 24 2005 |
Bibliographical note
Funding Information:We are grateful to B. B. Grebnev for identification of the ascidian. The research described in this publication was made possible in part by Grant NS-725.2003.4 of RFBR and a Grant from the Program ‘Molecular and cell biology of RAS’.
Keywords
- Cancer preventive activity
- Marine natural products
- Polyprenylated quinones
- Synthesis