Designing safer chemicals: Predicting the rates of metabolism of halogenated alkanes

Keyphrases

• Metabolism Rate 100%
• Safer Chemicals 100%
• Halogenated Alkanes 100%
• Cytochrome P450 (CYP450) 66%
• Inhalation Anesthetics 66%
• Hydrogen Abstraction 66%
• Computational Model 33%
• Computational Prediction 33%
• Rain 33%
• Activation Energy 33%
• Cytochrome P450 Enzymes 33%
• Enzyme Preparation 33%
• Isoflurane 33%
• Bromo 33%
• In Vitro Metabolism 33%
• Metabolic Rate 33%
• Fluoro 33%
• Chlorofluorocarbons 33%
• Desflurane 33%
• Sevoflurane 33%
• In Vitro Data 33%
• Rat Liver Microsomes 33%
• Biotransformation Rate 33%
• Cytochrome P450 2E1 (CYP2E1) 33%
• 1-chloro-2 33%
• Methoxyflurane 33%
• Chloroethane 33%
• Enflurane 33%
• Difluoro 33%
• 1,1,2,2-Tetrachloroethane 33%
• Trichloroethane 33%
• In Vitro Biotransformation 33%
• Pentafluoroethane 33%
• 1,2-dichloroethane 33%
• Human Enzymes 33%

Chemistry

• Alkane 100%
• Cytochrome P450 100%
• Inhalation Anaesthetic 66%
• 1,1,2,2-tetrachloroethane 66%
• Hydrogen Atom 66%
• Metabolic 33%
• Reaction Activation Energy 33%
• Chloroethane 33%
• 2-Chloro-1,1,1-trifluoroethane 33%
• 1,1-Dichloroethane 33%
• 1,2-Dichloroethane 33%
• 1,1,1-Trichloroethane 33%
• Isoflurane 33%
• Sevoflurane 33%
• Desflurane 33%
• Enflurane 33%
• Methoxyflurane 33%
• Hydrochlorofluorocarbon 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Alkane 100%
• Cytochrome P450 100%
• 1,1 Dichloro 2,2,2 Trifluoroethane 100%
• Inhalation Anesthetic Agent 66%
• Tetrachloroethane 66%
• Chloroethane 33%
• CYP2E1 33%
• Chlorofluorohydrocarbon 33%
• Isoflurane 33%
• Sevoflurane 33%
• Methoxyflurane 33%
• Enflurane 33%
• Desflurane 33%