A straight forward entry into nine membered B ring of eleutherobin as oxy analog and its cyctotoxic properties on HBL cell lines is described. Molecular modeling studies were carried out to ascertain the binding of the model compound to the active site of β-tubulin.
Bibliographical noteFunding Information:
V.J. and C.N.G. thank CSIR, New Delhi for the financial assistance. Research grants for the project from DST, New Delhi is acknowledged.
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