Design of parallel transmission radiofrequency pulses robust against respiration in cardiac MRI at 7 Tesla

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Purpose Two-spoke parallel transmission (pTX) radiofrequency (RF) pulses have been demonstrated in cardiac MRI at 7T. However, current pulse designs rely on a single set of B1+/B0 maps that may not be valid for subsequent scans acquired at another phase of the respiration cycle because of organ displacement. Such mismatches may yield severe excitation profile degradation. Methods B1+/B0 maps were obtained, using 16 transmit channels at 7T, at three breath-hold positions: exhale, half-inhale, and inhale. Standard and robust RF pulses were designed using maps obtained at exhale only, and at multiple respiratory positions, respectively. Excitation patterns were analyzed for all positions using Bloch simulations. Flip-angle homogeneity was compared in vivo in cardiac CINE acquisitions. Results Standard one- and two-spoke pTX RF pulses are sensitive to breath-hold position, primarily due to B1+ alterations, with high dependency on excitation trajectory for two spokes. In vivo excitation inhomogeneity varied from nRMSE = 8.2% (exhale) up to 32.5% (inhale) with the standard design; much more stable results were obtained with the robust design with nRMSE = 9.1% (exhale) and 10.6% (inhale). Conclusion A new pTX RF pulse design robust against respiration induced variations of B1+/B0 maps is demonstrated and is expected to have a positive impact on cardiac MRI in breath-hold, free-breathing, and real-time acquisitions. Magn Reson Med 74:1291-1305, 2015.

Original languageEnglish (US)
Pages (from-to)1291-1305
Number of pages15
JournalMagnetic resonance in medicine
Issue number5
StatePublished - Nov 2015

Bibliographical note

Publisher Copyright:
© 2014 Wiley Periodicals, Inc. © 2014 Wiley Periodicals, Inc.


  • 7 Tesla
  • RF pulse design
  • breath-hold
  • cardiac MRI
  • pTX
  • respiration
  • spoke pulses


Dive into the research topics of 'Design of parallel transmission radiofrequency pulses robust against respiration in cardiac MRI at 7 Tesla'. Together they form a unique fingerprint.

Cite this