Design of a 13C {1H} RF Probe for monitoring the in vivo metabolism of [1-13C]glucose in primate brain

B. E. Hammer, W. Sacks, R. E. Bigler, M. J. Hennessy, S. Sacks, A. Fleischer, P. B. Zanzonico

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The design of an RF probe suitable for obtaining proton-decoupled 13C spectra from a subhuman primate brain is described. Two orthogonal saddle coils, one tuned to the resonant frequency of 13C and the other to the resonant frequency of 1H, were used to monitor the in vivo metabolism of [1-13C]glucose in rhesus monkey brain at 2.1 T. Difference spectra showed the appearance of 13C-enriched glutamate and glutamine 30 to 40 min after a bolus injection of [1-13C]glucose.

Original languageEnglish (US)
Pages (from-to)1-5
Number of pages5
JournalMagnetic resonance in medicine
Volume13
Issue number1
DOIs
StatePublished - Jan 1 1990

Fingerprint Dive into the research topics of 'Design of a <sup>13</sup>C {<sup>1</sup>H} RF Probe for monitoring the in vivo metabolism of [1-<sup>13</sup>C]glucose in primate brain'. Together they form a unique fingerprint.

Cite this