Depressive symptoms in older versus younger people with epilepsy: Findings from an integrated epilepsy self-management clinical research dataset

Zaira Khalid, Hasina Momotaz, Farren Briggs, Kristin A. Cassidy, Naomi S. Chaytor, Robert T. Fraser, Mary R. Janevic, Barbara Jobst, Erica K. Johnson, Peter Scal, Tanya M. Spruill, Betsy K. Wilson, Martha Sajatovic

Research output: Contribution to journalArticle

Abstract

Aim: There are limited data on psychological outcomes in older people with epilepsy (PWE). This analysis, from a large pooled dataset of clinical studies from the Managing Epilepsy Well (MEW) Network, examined clinical variables including depressive symptom severity, quality of life and epilepsy self-management competency among older (age 55+) vs younger (<age 55) PWE. We were particularly interested in differences between older vs younger individuals with clinically significant depression. Methods: Analyses used baseline data from 9 MEW Network studies and examined demographic and clinical variables. Older vs younger individuals were compared and then we assessed groups with clinically significant depression vs those without clinically significant depression using the PHQ-9 and QOLIE-10 as a measure of quality of life. Results: The sample included 935 individuals. Compared to younger adults (n=774), the older group (n=161) had a better quality of life (p= 0.041) and more individuals without clinically significant depression (p=0.038). There was a trend for slightly lower depression severity scores (PHQ-9 total) (p=0.07) in the older group and a trend for fewer seizures (p=0.055) in older adults relative to younger adults. Conclusion: Compared to younger PWE, older PWE have less clinically significant depression and better quality of life. Future research needs to identify possible mechanisms underlying these differences.

Original languageEnglish (US)
Pages (from-to)981-988
Number of pages8
JournalJournal of Multidisciplinary Healthcare
Volume12
DOIs
StatePublished - Jan 1 2019

Keywords

  • Database
  • Depression
  • Epilepsy
  • Quality of life
  • Self-management

PubMed: MeSH publication types

  • Journal Article

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  • Cite this

    Khalid, Z., Momotaz, H., Briggs, F., Cassidy, K. A., Chaytor, N. S., Fraser, R. T., Janevic, M. R., Jobst, B., Johnson, E. K., Scal, P., Spruill, T. M., Wilson, B. K., & Sajatovic, M. (2019). Depressive symptoms in older versus younger people with epilepsy: Findings from an integrated epilepsy self-management clinical research dataset. Journal of Multidisciplinary Healthcare, 12, 981-988. https://doi.org/10.2147/JMDH.S227184