Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia

Keyphrases

• Regulatory T Cells 100%
• Acute Myeloid Leukemia 100%
• Cytotoxic T Cells 100%
• Tumor-associated 100%
• T Cell Immunotherapy 100%
• Cytotoxic T Lymphocytes 66%
• Leukemia Disease 25%
• Site of Disease 25%
• Interleukin-2 16%
• Tumor Burden 16%
• Diphtheria Toxin 16%
• Treg Depletion 16%
• Disease Burden 16%
• Tumor 8%
• Tumor Cells 8%
• Host Immune Response 8%
• Antitumor 8%
• Treg 8%
• Host Factors 8%
• Therapeutic Efficacy 8%
• Adoptive Transfer 8%
• Immune Resistance 8%
• Long-term Survival 8%
• Poor Response 8%
• Memory Response 8%
• Long-term Survivors 8%
• Systemic Model 8%
• Non-acute 8%
• T Lymphocyte Proliferation 8%
• Tumor-induced Immune Suppression 8%
• Leukemia Progression 8%
• Metastasis Sites 8%
• Regulatory T Cell(Treg) 8%
• Lymphocyte Infusion 8%

Immunology and Microbiology

• Regulatory T Cell 100%
• Cytotoxic T Cell 100%
• Myeloid 100%
• Immunotherapy 100%
• Immunity 16%
• Tumor Volume 16%
• Disease Burden 16%
• Denileukin Diftitox 16%
• Tumor Cell 8%
• Lymphocyte Proliferation 8%
• Long Term Survival 8%
• Host Factor 8%