Delivery versus Potency in Treating Brain Tumors: BI-907828, a MDM2-p53 Antagonist with Limited BBB Penetration but Significant In Vivo Efficacy in Glioblastoma

Wenjuan Zhang, Rachael A. Vaubel, Ju Hee Oh, Ann C. Mladek, Surabhi Talele, Wenqiu Zhang, Katie L. Waller, Danielle M. Burgenske, Jann N. Sarkaria, William F. Elmquist

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Pharmacology, Toxicology and Pharmaceutical Science