Delayed spine pruning of direct pathway spiny projection neurons in a mouse model of parkinson’s disease

Keyphrases

• 6-hydroxydopamine (6-OHDA) 9%
• 6-OHDA Lesion 9%
• Axospinous Synapses 18%
• Direct Pathway 100%
• Dopaminergic Neurons 9%
• Ex Vivo Brain Slices 9%
• Homeostatic Mechanisms 9%
• Indirect Pathway 27%
• Mouse Model 100%
• Nigrostriatal System 9%
• Parkinson's Disease Model 100%
• Parkinsonian State 18%
• Pathophysiology 9%
• Pruning 18%
• Specific Types 9%
• Spine 9%
• Spine Loss 27%
• Spine Pruning 100%
• Spiny Projection Neurons 100%
• Striatal 9%
• Synapse Elimination 9%
• Transgenic Mice 9%
• Two-photon Laser Scanning Microscopy 9%

Pharmacology, Toxicology and Pharmaceutical Science

• Confocal Microscopy 50%
• Dopamine Receptor Stimulating Agent 50%
• Elimination 50%
• Mouse Model 100%
• Oxidopamine 50%
• Parkinson's Disease 100%
• Pathophysiology 50%
• Transgenic Mouse 50%
• Two-Photon Microscopy 50%

Neuroscience

• Brain Slice 20%
• Dopaminergic Neuron 20%
• Oxidopamine 20%
• Parkinson's Disease 100%
• Scanning Electron Microscopy 20%
• Synapse 40%
• Vertebral Column 100%