Delayed spine pruning of direct pathway spiny projection neurons in a mouse model of parkinson’s disease

Keyphrases

• Mouse Model 100%
• Parkinson's Disease Model 100%
• Direct Pathway 100%
• Spine Pruning 100%
• Spiny Projection Neurons 100%
• Indirect Pathway 27%
• Spine Loss 27%
• Parkinsonian State 18%
• Pruning 18%
• Axospinous Synapses 18%
• Pathophysiology 9%
• Transgenic Mice 9%
• Striatal 9%
• Spine 9%
• Two-photon Laser Scanning Microscopy 9%
• Dopaminergic Neurons 9%
• Nigrostriatal System 9%
• Specific Types 9%
• Homeostatic Mechanisms 9%
• 6-hydroxydopamine (6-OHDA) 9%
• 6-OHDA Lesion 9%
• Synapse Elimination 9%
• Ex Vivo Brain Slices 9%

Pharmacology, Toxicology and Pharmaceutical Science

• Mouse Model 100%
• Parkinson's Disease 100%
• Elimination 50%
• Transgenic Mouse 50%
• Confocal Microscopy 50%
• Two-Photon Microscopy 50%
• Dopamine Receptor Stimulating Agent 50%
• Pathophysiology 50%
• Oxidopamine 50%

Neuroscience

• Parkinson's Disease 100%
• Synapse 100%
• Oxidopamine 50%
• Scanning Electron Microscopy 50%
• Brain Slice 50%
• Dopaminergic Neuron 50%