Delayed onset of suspected malignant hyperthermia during sevoflurane anesthesia in an afghan trauma patient: A case report

L. C D R Rafal Banek, L. C D R John Weatherwax, C. D R Dennis Spence, L. T C Susan Perry, Sheila Muldoon, John Capacchione

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Malignant hyperthermia (MH) is a rare pathologic hypermetabolic pharmacogenetic disorder of skeletal muscle calcium regulation following exposure to depolarizing muscle relaxants and/or volatile anesthetics. Although its pathogenesis is relatively well understood, there is wide variability in both the time of onset and the presentation of clinical signs and symptoms. In some circumstances the delayed onset of the hypermetabolic state may hinder timely recognition and treatment. Differential diagnosis of an MH crisis can be particularly challenging in a trauma patient, especially in an austere environment. This case report describes the presentation and management of a suspected case of MH in an Afghan national who underwent surgery following lower extremity trauma resulting from an improvised explosive device.

Original languageEnglish (US)
Pages (from-to)441-445
Number of pages5
JournalAANA Journal
Volume81
Issue number6
StatePublished - Dec 1 2013

Keywords

  • Emergency surgery
  • Malignant hyperthermia
  • Sevoflurane
  • Succinylcholine
  • Trauma

Fingerprint Dive into the research topics of 'Delayed onset of suspected malignant hyperthermia during sevoflurane anesthesia in an afghan trauma patient: A case report'. Together they form a unique fingerprint.

Cite this