Delayed Arterial Switch Operation for D-Transposition of the Great Arteries and Glucocorticoid Remediable Aldosteronism

Nofil Arain, Elizabeth Braunlin, James St Louis, Roosevelt Bryant

Research output: Contribution to journalReview article

Abstract

The Jatene arterial switch operation (ASO) for dextro-transposition of the great arteries is ideally performed within the first 2 weeks of life. Clinical circumstances, however, may dictate a delayed ASO and left ventricle “retraining” prior to the procedure. Glucocorticoid remediable aldosteronism (GRA) accounts for 0.5% to 1% of primary aldosteronism. It presents as severe hypertension in infants and children, with poor response to standard antihypertensive medications. To the authors’ knowledge, this is the first reported case of GRA in the context of transposition physiology. The management of GRA and a rationale for delayed ASO are discussed.

Original languageEnglish (US)
Pages (from-to)316-317
Number of pages2
JournalWorld Journal for Pediatric and Congenital Heart Surgery
Volume2
Issue number2
DOIs
StatePublished - Jan 1 2011

Fingerprint

Transposition of Great Vessels
Hyperaldosteronism
Antihypertensive Agents
Heart Ventricles
Hypertension
Glucocorticoid-Remediable Aldosteronism
Arterial Switch Operation

Keywords

  • arterial switch operation
  • comorbidity
  • congenital heart surgery
  • endocrinology
  • preconditioning

Cite this

Delayed Arterial Switch Operation for D-Transposition of the Great Arteries and Glucocorticoid Remediable Aldosteronism. / Arain, Nofil; Braunlin, Elizabeth; Louis, James St; Bryant, Roosevelt.

In: World Journal for Pediatric and Congenital Heart Surgery, Vol. 2, No. 2, 01.01.2011, p. 316-317.

Research output: Contribution to journalReview article

@article{09b3261c330540f5ae93c6854ba7d6cb,
title = "Delayed Arterial Switch Operation for D-Transposition of the Great Arteries and Glucocorticoid Remediable Aldosteronism",
abstract = "The Jatene arterial switch operation (ASO) for dextro-transposition of the great arteries is ideally performed within the first 2 weeks of life. Clinical circumstances, however, may dictate a delayed ASO and left ventricle “retraining” prior to the procedure. Glucocorticoid remediable aldosteronism (GRA) accounts for 0.5{\%} to 1{\%} of primary aldosteronism. It presents as severe hypertension in infants and children, with poor response to standard antihypertensive medications. To the authors’ knowledge, this is the first reported case of GRA in the context of transposition physiology. The management of GRA and a rationale for delayed ASO are discussed.",
keywords = "arterial switch operation, comorbidity, congenital heart surgery, endocrinology, preconditioning",
author = "Nofil Arain and Elizabeth Braunlin and Louis, {James St} and Roosevelt Bryant",
year = "2011",
month = "1",
day = "1",
doi = "10.1177/2150135110394217",
language = "English (US)",
volume = "2",
pages = "316--317",
journal = "World Journal for Pediatric and Congenital Hearth Surgery",
issn = "2150-1351",
publisher = "Sage Periodicals Press",
number = "2",

}

TY - JOUR

T1 - Delayed Arterial Switch Operation for D-Transposition of the Great Arteries and Glucocorticoid Remediable Aldosteronism

AU - Arain, Nofil

AU - Braunlin, Elizabeth

AU - Louis, James St

AU - Bryant, Roosevelt

PY - 2011/1/1

Y1 - 2011/1/1

N2 - The Jatene arterial switch operation (ASO) for dextro-transposition of the great arteries is ideally performed within the first 2 weeks of life. Clinical circumstances, however, may dictate a delayed ASO and left ventricle “retraining” prior to the procedure. Glucocorticoid remediable aldosteronism (GRA) accounts for 0.5% to 1% of primary aldosteronism. It presents as severe hypertension in infants and children, with poor response to standard antihypertensive medications. To the authors’ knowledge, this is the first reported case of GRA in the context of transposition physiology. The management of GRA and a rationale for delayed ASO are discussed.

AB - The Jatene arterial switch operation (ASO) for dextro-transposition of the great arteries is ideally performed within the first 2 weeks of life. Clinical circumstances, however, may dictate a delayed ASO and left ventricle “retraining” prior to the procedure. Glucocorticoid remediable aldosteronism (GRA) accounts for 0.5% to 1% of primary aldosteronism. It presents as severe hypertension in infants and children, with poor response to standard antihypertensive medications. To the authors’ knowledge, this is the first reported case of GRA in the context of transposition physiology. The management of GRA and a rationale for delayed ASO are discussed.

KW - arterial switch operation

KW - comorbidity

KW - congenital heart surgery

KW - endocrinology

KW - preconditioning

UR - http://www.scopus.com/inward/record.url?scp=84990393847&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84990393847&partnerID=8YFLogxK

U2 - 10.1177/2150135110394217

DO - 10.1177/2150135110394217

M3 - Review article

VL - 2

SP - 316

EP - 317

JO - World Journal for Pediatric and Congenital Hearth Surgery

JF - World Journal for Pediatric and Congenital Hearth Surgery

SN - 2150-1351

IS - 2

ER -