Delayed and recurrent intracranial hematomas related to disseminated intravascular clotting and fibrinolysis in head injury

H. H. Kaufman, J. L. Moake, J. D. Olson, M. E. Miner, Rene P Du Cret, J. L. Pruessner, P. L. Gildenberg

Research output: Contribution to journalArticlepeer-review

109 Scopus citations

Abstract

Twelve delayed or recurrent intracranial hematomas were seen in 340 patients with head injuries. Eleven of these hematomas were associated with clotting abnormalities suggesting disseminated intravascular clotting and fibrinolysis (DICF). Seven of 8 delayed traumatic intracerebral hematomas were associated with clotting abnormalities. Two of these were at ventriculostomy sites, which suggests an increased risk of bleeding in association with the insertion of ventricular catheters in patients with DICF. There were 2 delayed hematomas, 1 under a fracture and the other on the side opposite a craniotomy that had been made to treat an intracerebral hematoma, and there were 2 postoperative epidural hematomas. No postoperative hematomas occurred in the absence of DICF. DICF is a major factor in the development of delayed and recurrent intracranial hematomas in patients with head injuries.

Original languageEnglish (US)
Pages (from-to)445-449
Number of pages5
JournalUnknown Journal
Volume7
Issue number5
DOIs
StatePublished - Jan 1 1980

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