During the past year, the field of dehalogenation has seen rapid progress in the identification of novel organisms, the sequencing of new genes, and the delineation of mechanisms for important enzymes. Newly identified anaerobic organisms are beginning to offer insights into a previously obscure, but important, group of bacteria involved in environmental dehalogenation. An important series of X-ray structure determinations have provided key knowledge for understanding and, ultimately, engineering biodehalogenation catalysis.
Bibliographical noteFunding Information:
I thank the many talented coworkers in my laboratory who have contributed to studies on biodehalogenation. I acknowledge financial support from the National Institutes of Health, the Air Force Office of Scientific Research, and the Environmental Protection Agency.
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