Deficits in preference-based health-related quality of life after complications associated with tibial fracture

I. L. Gitajn, A. J. Titus, A. N. Tosteson, S. Sprague, K. Jeray, B. Petrisor, M. Swiontkowski, M. Bhandari, G. Slobogean

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Aims: The aims of this study were to quantify health state utility values (HSUVs) after a tibial fracture, investigate the effect of complications, to determine the trajectory in HSUVs that result in these differences and to quantify the quality-adjusted life years (QALYs) experienced by patients. Patients and Methods: This is an analysis of 2138 tibial fractures enrolled in the Fluid Lavage of Open Wounds (FLOW) and Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures (SPRINT) trials. Patients returned for follow-up at two and six weeks and three, six, nine and 12 months. Short-Form Six-Dimension (SF-6D) values were calculated and used to calculate QALYs. Results: Compared with those who did not have a complication, those with a complication treated either nonoperatively or operatively had lower HSUVs at all times after two weeks. The HSUVs improved in all patients with the passage of time. However, they did not return to the remembered baseline preinjury values nor to US age-adjusted normal values by 12 months after the injury. Conclusion: While the acute fracture and complications may have resolved clinically, the detrimental effect on a patient's quality of life persists up to 12 months after the injury.

Original languageEnglish (US)
Pages (from-to)1227-1233
Number of pages7
JournalBone and Joint Journal
Issue number9
StatePublished - Sep 2018

Bibliographical note

Publisher Copyright:
© 2018 The British Editorial Society of Bone & Joint Surgery.


Dive into the research topics of 'Deficits in preference-based health-related quality of life after complications associated with tibial fracture'. Together they form a unique fingerprint.

Cite this