Defective neutrophil function in workers occupationally exposed to hexachlorobenzene

Mls Queiroz, C. Bincoletto, Rcr Perlingeiro, C. A. Souza, H. Toledo

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


In this work we have studied the respiratory burst and chemotaxis of polymorphonuclear leukocytes from 51 workers exposed to chlorinated compounds, which were compared with those of non-exposed, age- and sex- matched invididuals. These two neutrophil functions were significantly reduced as compared to controls. No correlation was observed between the length of exposure, hexachlorobenzene (HCB) blood concentrations and neu trophil chemotaxis or the extent of nitroblue tetrazolium reduction.

Original languageEnglish (US)
Pages (from-to)322-326
Number of pages5
JournalHuman & Experimental Toxicology
Issue number6
StatePublished - Jun 1997

Bibliographical note

Copyright 2016 Elsevier B.V., All rights reserved.


  • chemotaxis
  • hexachlorobenzene
  • humans
  • respiratory burst


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