Dedifferentiation and neuronal repression define familial Alzheimer's disease

Keyphrases

• Early Alzheimer's Disease 100%
• Dedifferentiation 100%
• Familial Alzheimer's Disease 100%
• Alzheimer's Disease 66%
• Chromatin Structure 66%
• Human Induced Pluripotent Stem Cell-derived Neurons 66%
• Omics Approaches 33%
• Histone Methylation 33%
• System Level 33%
• Therapeutic Intervention 33%
• Disease Genes 33%
• ChIP-seq Analysis 33%
• RNA Sequencing (RNA-seq) 33%
• Ectoderm 33%
• Unmet Needs 33%
• Post-transcriptional Modification 33%
• Causative Mechanism 33%
• Neuron Model 33%
• Neuronal Identity 33%
• ATAC-seq 33%
• Alzheimer's Disease Patient 33%
• Gene Regulatory Programs 33%
• Cell State 33%

Biochemistry, Genetics and Molecular Biology

• Cell Dedifferentiation 100%
• Human Induced Pluripotent Stem Cell 100%
• Locus Control Region 50%
• Ectoderm 50%
• RNA Sequencing 50%
• ATAC-Seq 50%
• Histone Methylation 50%
• Precursor 50%
• Epiblast 50%