Abstract
Evidence has accumulated supporting the relationship between the use of 7-valent pneumococcal conjugate vaccine (PCV7) in children and a decline in invasive pneumococcal disease (IPD) in the elderly. We conducted a state-level analysis of vaccination coverage rates among children 19-35 months of age and IPD hospitalization rates among elderly Medicare beneficiaries. Simple correlations were suggestive of a negative relationship. Multivariate analysis using a state fixed-effect model which helped control for the time invariant factors at the state level also indicated a negative relationship, and it was statistically significant, p = 0.035. The relationship between the use of 23-valent pneumococcal polysaccharide vaccine (PPV23) and IPD hospitalizations was not statistically significant using either method.
Original language | English (US) |
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Pages (from-to) | 5609-5614 |
Number of pages | 6 |
Journal | Vaccine |
Volume | 24 |
Issue number | 27-28 |
DOIs | |
State | Published - Jul 7 2006 |
Bibliographical note
Funding Information:Financial support was provided by the Centers for Medicare and Medicaid Services contract CMS 500-01-0043.
Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
Keywords
- Elderly
- Invasive pneumococcal disease
- Pneumonia vaccine