TY - JOUR
T1 - Decreased gray matter in normal aging
T2 - An in vivo magnetic resonance study
AU - Lim, K. O.
AU - Zipursky, R. B.
AU - Watts, M. C.
AU - Pfefferbaum, A.
PY - 1992
Y1 - 1992
N2 - Using in vivo magnetic resonance (MR) images, the percentages of gray matter, white matter, and cerebrospinal fluid (CSF) in the brains of 8 young and 6 elderly normal male community volunteers were quantified. Compared with the young men, the elderly men had a significantly lower percentage of gray matter (p < .01) and higher percentage of CSF (p < .01). The percentage of white matter was not significantly different between the two groups. This finding suggests that the age-related decrease in brain tissue is chiefly due to loss of gray matter.
AB - Using in vivo magnetic resonance (MR) images, the percentages of gray matter, white matter, and cerebrospinal fluid (CSF) in the brains of 8 young and 6 elderly normal male community volunteers were quantified. Compared with the young men, the elderly men had a significantly lower percentage of gray matter (p < .01) and higher percentage of CSF (p < .01). The percentage of white matter was not significantly different between the two groups. This finding suggests that the age-related decrease in brain tissue is chiefly due to loss of gray matter.
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U2 - 10.1093/geronj/47.1.B26
DO - 10.1093/geronj/47.1.B26
M3 - Article
C2 - 1730845
AN - SCOPUS:0026508904
SN - 0022-1422
VL - 47
SP - B26-B30
JO - Journal of Gerontology: Social Sciences
JF - Journal of Gerontology: Social Sciences
IS - 1
ER -