Abstract
A simple platform for carbocycle synthesis by Knoevenagel adduct deconjugative alkylation/Heck reaction is described. Deconjugative alkylation of Knoevenagels adducts is two-fold synthetically enabling because C-C bond formation is (1) operationally simple due to the ease of Knoevenagel adduct carbanion generation and (2) results in alkene migration, which poises the substrate for cyclization. Furthermore, the gem-dinitrile moiety serves as a functional group for synthetic manipulation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 69-75 |
| Number of pages | 7 |
| Journal | Organic and Biomolecular Chemistry |
| Volume | 15 |
| Issue number | 1 |
| DOIs | |
| State | Published - 2017 |
| Externally published | Yes |
Bibliographical note
Publisher Copyright:© The Royal Society of Chemistry.
Fingerprint
Dive into the research topics of 'Deconjugative alkylation/Heck reaction as a simple platform for dihydronaphthalene synthesis'. Together they form a unique fingerprint.Cite this
- APA
- Standard
- Harvard
- Vancouver
- Author
- BIBTEX
- RIS