Abstract
How tumor cells gain resistance to drugs is critically important to elucidate for developing better cancer therapy. In this issue of Blood, Wray and colleagues have identified a mechanism whereby acute leukemia cells use a stimulator of topoisomerase II activity to allow proliferation despite drug inhibition of this essential enzyme.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1721-1722 |
| Number of pages | 2 |
| Journal | Blood |
| Volume | 114 |
| Issue number | 9 |
| DOIs |
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| State | Published - 2009 |
