DEB-FAPy-dG Adducts of 1,3-Butadiene: Synthesis, Structural Characterization, and Formation in 1,2,3,4-Diepoxybutane Treated DNA**

Keyphrases

• Diepoxybutane 100%
• Structural Characterization 100%
• 1,3-Butadiene 100%
• Structural Formation 100%
• Epoxy 10%
• Alkylation 10%
• Purine 10%
• Circulating Tumor DNA (ctDNA) 10%
• Ring Opening 10%
• Monooxygenase 10%
• Metabolic Activation 10%
• Diepoxide 10%
• Imidazole Ring 10%
• Positive Charge 10%
• Human Carcinogen 10%
• Diamino 10%
• 1-Propanol 10%
• Depurination 10%
• Base Hydrolysis 10%
• Alkaline Condition 10%
• Authentic Standards 10%
• Reactive Electrophiles 10%
• Guanine Base 10%
• First Synthesis 10%
• Formamidopyrimidines 10%
• HR-ESI-MS 10%
• Cytochrome 450 10%
• MS Method 10%
• Heterocycles 10%
• NanoLC 10%

Pharmacology, Toxicology and Pharmaceutical Science

• 1,3-Butadiene 100%
• Diepoxybutane 100%
• Carcinogen 10%
• Unspecific Monooxygenase 10%
• Electrophile 10%
• Propanol 10%
• Base 10%
• Guanine 10%
• Cytochrome 10%
• Imidazole 10%
• Purine 10%