De novo formation of immune complexes in toman kidney allografts

Wei Kuang Wu; Bernice K. Noble; S. Michael Mauer; Felix Milgrom

doi:10.3109/08820138509042008

De novo formation of immune complexes in toman kidney allografts

Wei Kuang Wu, Bernice K. Noble, S. Michael Mauer, Felix Milgrom

Pediatric Nephrology

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Abstract

Cryostat sections of 11 rejected human renal grafts were selected for positive results in immunofluorescence tests. Immune complexes were detected in glomerular basement membrane (9 cases), tubular basement membrane (3 cases), and vessels (5 cases). Preincubation of the sections with FII of pooled human serum, but not of rabbit serum, prevented the staining of immune complexes for human IgG. These findings were interpreted by the assumption that most complexes under study were produced by reaction of the patient's altered IgG with the rheumatoid-like factor of IgG variety.

Original language	English (US)
Pages (from-to)	145-149
Number of pages	5
Journal	Immunological Investigations
Volume	14
Issue number	2
DOIs	https://doi.org/10.3109/08820138509042008
State	Published - 1985

Bibliographical note

Funding Information:
This work was supported by NIH Research Grant AM-17317.

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title = "De novo formation of immune complexes in toman kidney allografts",

abstract = "Cryostat sections of 11 rejected human renal grafts were selected for positive results in immunofluorescence tests. Immune complexes were detected in glomerular basement membrane (9 cases), tubular basement membrane (3 cases), and vessels (5 cases). Preincubation of the sections with FII of pooled human serum, but not of rabbit serum, prevented the staining of immune complexes for human IgG. These findings were interpreted by the assumption that most complexes under study were produced by reaction of the patient's altered IgG with the rheumatoid-like factor of IgG variety.",

author = "Wu, {Wei Kuang} and Noble, {Bernice K.} and Mauer, {S. Michael} and Felix Milgrom",

note = "Funding Information: This work was supported by NIH Research Grant AM-17317.",

year = "1985",

doi = "10.3109/08820138509042008",

language = "English (US)",

volume = "14",

pages = "145--149",

journal = "Immunological Investigations",

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T1 - De novo formation of immune complexes in toman kidney allografts

AU - Wu, Wei Kuang

AU - Noble, Bernice K.

AU - Mauer, S. Michael

AU - Milgrom, Felix

N1 - Funding Information: This work was supported by NIH Research Grant AM-17317.

PY - 1985

Y1 - 1985

N2 - Cryostat sections of 11 rejected human renal grafts were selected for positive results in immunofluorescence tests. Immune complexes were detected in glomerular basement membrane (9 cases), tubular basement membrane (3 cases), and vessels (5 cases). Preincubation of the sections with FII of pooled human serum, but not of rabbit serum, prevented the staining of immune complexes for human IgG. These findings were interpreted by the assumption that most complexes under study were produced by reaction of the patient's altered IgG with the rheumatoid-like factor of IgG variety.

AB - Cryostat sections of 11 rejected human renal grafts were selected for positive results in immunofluorescence tests. Immune complexes were detected in glomerular basement membrane (9 cases), tubular basement membrane (3 cases), and vessels (5 cases). Preincubation of the sections with FII of pooled human serum, but not of rabbit serum, prevented the staining of immune complexes for human IgG. These findings were interpreted by the assumption that most complexes under study were produced by reaction of the patient's altered IgG with the rheumatoid-like factor of IgG variety.

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JO - Immunological Investigations

JF - Immunological Investigations

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ER -

De novo formation of immune complexes in toman kidney allografts

Abstract

Bibliographical note

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