Dam1 complexes go it alone on disassembling microtubules

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Kinetochores maintain a mechanical grip on disassembling microtubule plus ends, possibly through a 16-member Dam1 ring that acts as a sliding clamp. It turns out, however, that a ring is not required for maintaining grip: individual Dam1 complexes in vitro can diffuse on the microtubule lattice and track shortening microtubule tips.

Original languageEnglish (US)
Pages (from-to)379-381
Number of pages3
JournalNature Cell Biology
Issue number4
StatePublished - Aug 11 2008


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