Abstract
Kinetochores maintain a mechanical grip on disassembling microtubule plus ends, possibly through a 16-member Dam1 ring that acts as a sliding clamp. It turns out, however, that a ring is not required for maintaining grip: individual Dam1 complexes in vitro can diffuse on the microtubule lattice and track shortening microtubule tips.
Original language | English (US) |
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Pages (from-to) | 379-381 |
Number of pages | 3 |
Journal | Nature Cell Biology |
Volume | 10 |
Issue number | 4 |
DOIs | |
State | Published - 2008 |