Abstract
[D-Thr2, Thz5]-enkephalinamide administered orally or subcutaneously inhibited the tail-flick response to heat stimuli in mice. On a molar basis, this peptide was found to be 1.5-1.7 times more potent than morphine by oral administration.
Original language | English (US) |
---|---|
Pages (from-to) | 2053-2056 |
Number of pages | 4 |
Journal | Life Sciences |
Volume | 23 |
Issue number | 20 |
DOIs | |
State | Published - Nov 13 1978 |
Bibliographical note
Funding Information:This work was supported in part by grants from NIDA No . DA-01314 (to L-F . T,), DA-00564 (to H .H .L .), NIMH MH-30245 and Hormone Research Foundation (to C .H .L .) .