d-Amphetamine raises cortisol levels in schizophrenic patients with and without chronic naltrexone pretreatment

D. P. van Kammen, S. Charles Schulz

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Five drug-free schizophrenic patients received an infusion of 20 mg d-amphetamine and placebo on separate days in a pilot study. Plasma cortisol levels rose significantly at 1 and 2 hours after d-amphetamine compared to following placebo. A repeat infusion of d-amphetamine during naltrexone treatment led to a similar increase in cortisol concentrations.

Original languageEnglish (US)
Pages (from-to)35-43
Number of pages9
JournalJournal of Neural Transmission
Volume64
Issue number1
DOIs
StatePublished - Mar 1 1985

Keywords

  • cortisol
  • d-amphetamine
  • naltrexone
  • schizophrenia
  • stress

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