Cytotoxicity of urushiols isolated from sap of Korean lacquer tree (Rhus vernicifera stokes)

Dong Ho Hong, Sang Bae Han, Chang Woo Lee, Se Hyung Park, Young Jin Jeon, Myong Jo Kim, Sang Soo Kwak, Hwan Mook Kim

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Abstract

Cytotoxicities of four urushiols, congeners isolated from the sap of Korean lacquer tree (Rhus vernicifera Stokes), to 29 human cancer cell lines originated from 9 organs were evaluated. Their values of 50% growth inhibition were below 4 μg/ml, and showed cell line specific cytotoxicity. The present result is the first report on the cytotoxicity of urushiols suggesting that they would have an anticancer activity to human cancer cells.

Original languageEnglish (US)
Pages (from-to)638-641
Number of pages4
JournalArchives of Pharmacal Research
Volume22
Issue number6
DOIs
StatePublished - Dec 1999

Keywords

  • Cytotoxicity
  • Human Caner Cells
  • Urushiols

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    Hong, D. H., Han, S. B., Lee, C. W., Park, S. H., Jeon, Y. J., Kim, M. J., Kwak, S. S., & Kim, H. M. (1999). Cytotoxicity of urushiols isolated from sap of Korean lacquer tree (Rhus vernicifera stokes). Archives of Pharmacal Research, 22(6), 638-641. https://doi.org/10.1007/BF02975339