Cytotoxic hydroazulene diterpenes from the brown alga Cystoseira myrica

Seif Eldin N. Ayyad, Osama B. Abdel-Halim, W. Thomas Shier, Thomas R. Hoye

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


Cytotoxicity-guided fractionation of the alcohol extract of the brown alga, Cystoseira myrica, afforded four new cytotoxic hydroazulene diterpenes, dictyone acetate (2), dictyol F monoacetate (4), isodictytriol monoacetate (6), and cystoseirol monoacetate (8), together with two known cytotoxic hydroazulene diterpenes, pachydictyol A (1) and dictyone (3). The constitution of each isolated compound has been determined on the basis of spectroscopic and chemical evidence.

Original languageEnglish (US)
Pages (from-to)33-38
Number of pages6
JournalZeitschrift fur Naturforschung - Section C Journal of Biosciences
Issue number1-2
StatePublished - 2003


  • Cystoseira
  • Cytotoxic
  • Hydroazulenes


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