Cytokine expression in the mouse brain in response to immune activation by Corynebacterium parvum

W. S. Sheng; S. Hu; J. M. Ding; C. C. Chao; P. K. Peterson

doi:10.1128/CDLI.8.2.446-448.2001

Cytokine expression in the mouse brain in response to immune activation by Corynebacterium parvum

W. S. Sheng, S. Hu, J. M. Ding, C. C. Chao, P. K. Peterson

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Abstract

Cytokine expression in the brain has been suggested to mediate various sickness behaviors. Here we report that intraperitoneal injection of a Corynebacterium parvum antigen in C57BL/6 mice was followed by prolonged upregulation of cytokines in the cerebral cortex and subcortical structures in a time course that coincided with reduced spontaneous running activity.

Original language	English (US)
Pages (from-to)	446-448
Number of pages	3
Journal	Clinical and Diagnostic Laboratory Immunology
Volume	8
Issue number	2
DOIs	https://doi.org/10.1128/CDLI.8.2.446-448.2001
State	Published - 2001

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abstract = "Cytokine expression in the brain has been suggested to mediate various sickness behaviors. Here we report that intraperitoneal injection of a Corynebacterium parvum antigen in C57BL/6 mice was followed by prolonged upregulation of cytokines in the cerebral cortex and subcortical structures in a time course that coincided with reduced spontaneous running activity.",

author = "Sheng, {W. S.} and S. Hu and Ding, {J. M.} and Chao, {C. C.} and Peterson, {P. K.}",

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AU - Peterson, P. K.

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AB - Cytokine expression in the brain has been suggested to mediate various sickness behaviors. Here we report that intraperitoneal injection of a Corynebacterium parvum antigen in C57BL/6 mice was followed by prolonged upregulation of cytokines in the cerebral cortex and subcortical structures in a time course that coincided with reduced spontaneous running activity.

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Cytokine expression in the mouse brain in response to immune activation by Corynebacterium parvum

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