Cytochrome P-450 mediates tissue-damaging hydroxyl radical formation during reoxygenation of the kidney

Keyphrases

• Cytochrome P450 (CYP450) 100%
• Kidney 100%
• Deoxygenation 100%
• Hydroxyl Radical Generation 100%
• Ischemia-reperfusion Injury 28%
• Cell Injury 28%
• Fenton Reaction 28%
• Cimetidine 28%
• Hypoxia-reoxygenation 28%
• Superoxide Ion 28%
• Biomolecules 14%
• Hypoxia 14%
• Oxygen Radicals 14%
• Protective Effect 14%
• Glomerular Filtration Rate 14%
• Primary Culture 14%
• Kidney Cells 14%
• Catalytic Function 14%
• Radical Formation 14%
• Renal Tubular Epithelial Cells 14%
• Bleomycin 14%
• Hydroxyl Radical 14%
• Xanthine Oxidase 14%
• Ketoconazole 14%
• Reduced Iron 14%
• Piperonyl Butoxide 14%
• O2 Production 14%
• Renal Reperfusion 14%
• Radical Generation 14%
• Catalytic Iron 14%
• Iron Release 14%
• Heme Moiety 14%
• Renal Artery Obstruction 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Cytochrome P450 100%
• Hydroxyl Radical 100%
• Cytochrome P450 Inhibitor 80%
• Hypoxia 60%
• Superoxide 40%
• Cimetidine 40%
• Injury 40%
• Fenton Reaction 40%
• Reperfusion Injury 40%
• Primary Culture 20%
• Oxygen Radical 20%
• Transition Element 20%
• Ketoconazole 20%
• Piperonyl Butoxide 20%
• Bleomycin Iron 20%
• Kidney Artery Stenosis 20%
• Heme 20%
• Xanthine Oxidase 20%

Biochemistry, Genetics and Molecular Biology

• Cytochrome 100%
• Reoxygenation 100%
• Cytochrome P450 Inhibitor 57%
• Fenton Reaction 28%
• Reperfusion 28%
• Cimetidine 28%
• Cell Damage 28%
• Catalysis 14%
• In Vivo Study 14%
• Bleomycin 14%
• Primary Culture 14%
• Glomerulus Filtration 14%
• Xanthine Oxidase 14%