Keyphrases
Cytochrome P450 (CYP450)
100%
Esters
100%
Hydroxylation
100%
Phenyl
100%
Carboxylic Acid Esters
100%
Hantzsch 1,4-dihydropyridines
100%
Ester Cleavage
100%
3,5-Pyridinedicarboxylic Acid
100%
Methyl
83%
Hydroxymethyl
83%
Dimethyl
50%
Ethyl Esters
50%
Rat Liver
33%
Lactones
33%
Kinetic Isotope Effect
33%
Diester
33%
Catalytic Oxidation
16%
Deuterium
16%
Isotope Effect
16%
Deuteration
16%
Hydroxylated
16%
NF-B
16%
Ester Group
16%
Methyl Groups
16%
Pyridine
16%
Deuterium Isotope Effect
16%
Rat Liver Microsomes
16%
Reconstituted System
16%
Intrinsic Kinetics
16%
Isotopically Sensitive Branching
16%
Metabolic Switch
16%
Deuterium Isotope
16%
Competitive Experiments
16%
Cyclic Lactones
16%
Tritium Isotope
16%
Carboxylic Esters
16%
Chemistry
Pyridinedicarboxylic Acid
100%
Carboxylic Acid
100%
Cytochrome P450
100%
hydroxylation
100%
cleavage of esters
100%
Deuterium
66%
Ethyl Ester
50%
Lactone
50%
Isotope Effect
50%
Diester
33%
Deesterification
33%
Metabolic
16%
Kinetic Isotope Effect
16%
Methyl Group
16%
Carboxylic Ester
16%
Tritium
16%
Pharmacology, Toxicology and Pharmaceutical Science
Cytochrome P450
100%
Ester
100%
Deuterium
100%
Lactone
75%
Methyl Group
25%
Nicotinyl Alcohol
25%
Tritium
25%