Cystic variant of calcifying epithelial odontogenic tumor

Rajaram Gopalakrishnan, Susan Simonton, Michael D Rohrer, Ioannis G Koutlas

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Calcifying epithelial odontogenic tumor (CEOT) is a benign, locally aggressive odontogenic neoplasm characterized by sheets and nests of epithelial cells with deeply eosinophilic or occasionally clear cytoplasm, calcifications, and eosinophilic amorphous material that stains positive for amyloid. Although many cases of CEOT are associated with impacted teeth and occasionally appear radiographically as dentigerous cysts, a true cystic variant has not been previously reported. We report a 15-year-old white male with a large cystic maxillary lesion that filled most of the left maxillary sinus. It deformed the medial wall, the inferior orbital floor, and caused narrowing of the left inferior meatus. Histologically, the cystic lining showed characteristics of CEOT. An intraluminal component that featured histologic characteristics of CEOT was identified during surgery. The lesion was enucleated and the postsurgical course of the patient was uneventful. Because follow-up has been for less than 1 year, a meaningful long-term prognosis cannot be determined at present. However, the patient has not reported any symptoms or signs of recurrence during the follow-up period.

Original languageEnglish (US)
Pages (from-to)773-777
Number of pages5
JournalOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology
Issue number6
StatePublished - Dec 2006

Bibliographical note

Copyright 2008 Elsevier B.V., All rights reserved.


Dive into the research topics of 'Cystic variant of calcifying epithelial odontogenic tumor'. Together they form a unique fingerprint.

Cite this